a chemical with sporicidal properties is

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Few chemical biocides are actively sporocidal,and many of the disinfectants in use in hospitals are capable only of sporostasis. Examples includephenols,cresols,chlorhexidine,quaternary ammonium compounds and sub-lethal concentrations of chlorine-releasing agents and gluteraldehyde.

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  • Do chemical agents have sporicidal activity?

  • Comparatively few chemical agents, however, possess sporicidal activity (Waites and Bayliss, 1980; Russell, 1982a; Gould. 1983), although most compounds appear capable of inhibiting either germination or outgrowth of spores in their development into vegetative cells.

  • What is the difference between sporicidal and sterilant?

  • Sporicidal Agent鈥擜n agent that destroys bacterial and fungal spores when used in sufficient concentration for a specified contact time. It is expected to kill all vegetative microorganisms. Sterilant鈥擜n agent that destroys all forms of microbial life including fungi, viruses, and all forms of bacteria and their spores.

  • Why are bacterial spores so resistant to chemical agents?

  • Bacterial spores are highly resistant to a wide array of chemical and physical agents, due to their specialised chemical and physical structure. Clostridium difficile spores are of considerable importance from an infection control perspective, since this organism is the most common cause of nosocomial diarrhoea.

  • How do bacterial spores respond to biocides?

  • Bacterial spores are among the most resistant of all living cells to biocides, although the response depends on the stage of sporulation. The development of resistance to some agents such as chlorhexidine occurs much earlier in sporulation than does resistance to glutaraldehyde, which is a very late 鈥?/div>Bacterial spores and chemical sporicidal agents

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